SPARCing the clot

Clot retraction facilitates clot lysis.

Platelet facilitation of clot lysis was studied using the dilute clot lysis assay, a standardized assay for fibrinolysis shown to correlate with the development of postoperative deep vein thrombosis. Clots prepared from dilute platelet poor plasma showed prolonged clot lysis when compared with clots prepared in a similar fashion from dilute platelet rich plasma. Since in the presence of platele...

Feasibility of recording clot lysis with the thermometric clot detector.

Currently, the study of fibrinolysis is beset by problems of methodology (1 ). Disadvantages of many of the present methods for measurement of clot lysisincluding lysis time for the dilute blood clot, thromboelastography, euglobulin clot lysis, fibrin plate method, and caseinolytic assay (1 )-are imprecision of results and time required to perform the test (2). The electromechanical lysis timer...

The Vanishing Clot.

A 57 year-old woman with a history of a pulmonary embolus and deep vein thrombosis, on warfarin, presented with the acute onset of right hemiparesis, aphasia, and altered mental status. Her NIH Stroke Scale was 20. Her INR was found to be subtherapeutic at 1.5. The initial non-contrast head CT showed extensive clot in the M1 segment of the left middle cerebral artery (MCA) (arrow, Figure 1A). I...

Electrolytic resistance of the blood clot; resistance clotting time, onset of clot retraction and the clot resistance.

I N THE previous paper a technique for the determination of the electrolytic resistance of the blood clot was presented (I). The present paper deals with the variations in the electrolytic resistance of the blood clot over a 40. to &-hour period, and with the physiological significance of certain measurements of the resistance. The curve of the resistance against time will be called the electro...

Clot firmness.